Skinner-Adams, T. S.: search on Z-Library

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1

Drug repurposing and human parasitic protozoan diseases

Andrews, Katherine T., Fisher, Gillian, Skinner-Adams, Tina S.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

2

Plagiarism

Paula E. Brentlinger, Christopher B. Behrens, Mark A. Micek, Richard W. Steketee, Katherine T. Andrews, Tina S. Skinner-Adams, Donald L. Gardiner, James S. McCarthy, Sunil Parikh, Feiko ter Kuile, Joh

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

3

In vitro antimalarial activity of retinoids and the influence of selective retinoic acid receptor antagonists

J. Hamzah, T.S. Skinner-Adams, T.M.E. Davis

Journal:

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

4

Aminopeptidases of Malaria Parasites: New Targets for Chemotherapy

R. Trenholme, Katharine, L. Brown, Christopher, S. Skinner-Adams, Tina, Stack, Colin, Lowther, Jonathan, To, Joyce, W. Robinson, Mark, M. Donnelly, Sheila, P. Dalton, John, L. Gardiner, Donald

Journal:

Infectious Disorders - Drug Targets(Formerly Current Drug Targets - Infectious Disorders)

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

5

Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials

Tina S. Skinner-Adams, Colin M. Stack, Katharine R. Trenholme, Chris L. Brown, Jolanta Grembecka, Jonathan Lowther, Artur Mucha, Marcin Drag, Pawel Kafarski, Sheena McGowan, James C. Whisstock, Donald

Journal:

Trends in Biochemical Sciences

Year:

2010

Language:

english

File:

PDF, 824 KB

english, 2010

6

Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

Keough, Dianne T., Hocková, Dana, Holý, Antonín, Naesens, Lieve M. J., Skinner-Adams, Tina S., Jersey, John de, Guddat, Luke W.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.15 MB

english, 2009

7

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

McGowan, S., Porter, C. J., Lowther, J., Stack, C. M., Golding, S. J., Skinner-Adams, T. S., Trenholme, K. R., Teuscher, F., Donnelly, S. M., Grembecka, J., Mucha, A., Kafarski, P., DeGori, R., Buckle

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 780 KB

english, 2009

8

Antiplasmodial and Antioxidant Isofuranonaphthoquinones from the Roots of Bulbine capitata

Bezabih, Merhatibeb, Abegaz, Berhanu M., Dufall, Kitiya, Croft, Kevin, Skinner-Adams, Tina, Davis, Timothy M. E.

Journal:

Year:

2001

Language:

english

File:

PDF, 210 KB

english, 2001

9

Defining the targets of antiparasitic compounds

Skinner-Adams, Tina S., Sumanadasa, Subathdrage D.M., Fisher, Gillian M., Davis, Rohan A., Doolan, Denise L., Andrews, Katherine T.

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 533 KB

english, 2016

10

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A–D

Schwartz, Brett, Coster, Mark, Skinner-Adams, Tina, Andrews, Katherine, White, Jonathan, Davis, Rohan

Journal:

Year:

2015

Language:

english

File:

PDF, 271 KB

english, 2015

11

HIV and malaria co-infection: interactions and consequences of chemotherapy

T.S. Skinner-Adams, J.S. McCarthy, D.L. Gardiner, K.T. Andrews

Journal:

Trends in Parasitology

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

12

HIV-Malaria Interactions: Don't Forget the Drugs

Andrews, K. T., Gatton, M. L., Skinner-Adams, T. S., McCarthy, J. S., Gardiner, , D. L., Abu-Raddad, L. J., Patnaik, P., Kublin, J. G.

Journal:

Year:

2007

Language:

english

File:

PDF, 414 KB

english, 2007

13

Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites: TARGET FOR THE ANTIMALARIAL ACTIVITY OF BESTATIN

Gardiner, D. L., Trenholme, K. R., Skinner-Adams, T. S., Stack, C. M., Dalton, J. P.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 724 KB

english, 2006

14

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

Skinner-Adams, Tina S., Fisher, Gillian M., Riches, Andrew G., Hutt, Oliver E., Jarvis, Karen E., Wilson, Tony, von Itzstein, Mark, Chopra, Pradeep, Antonova-Koch, Yevgeniya, Meister, Stephan, Winzele

Journal:

Communications Biology

Year:

2019

File:

PDF, 1.17 MB

2019

15

Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum

Sauer, B., Skinner-Adams, T.S., Bouchut, A., Chua, M.J., Pierrot, C., Erdmann, F., Robaa, D., Schmidt, M., Khalife, J., Andrews, K.T., Sippl, W.

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

16

Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues

Andrews, K. T., Tran, T. N., Lucke, A. J., Kahnberg, P., Le, G. T., Boyle, G. M., Gardiner, D. L., Skinner-Adams, T. S., Fairlie, D. P.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

17

Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors

Hansen, Finn K., Skinner-Adams, Tina S., Duffy, Sandra, Marek, Linda, Sumanadasa, Subathdrage D. M., Kuna, Krystina, Held, Jana, Avery, Vicky M., Andrews, Katherine T., Kurz, Thomas

Journal:

Year:

2014

Language:

english

File:

PDF, 325 KB

english, 2014

18

Synergistic Interactions of the Antiretroviral Protease Inhibitors Saquinavir and Ritonavir with Chloroquine and Mefloquine against Plasmodium falciparum In Vitro

Skinner-Adams, T. S., Andrews, K. T., Melville, L., McCarthy, J., Gardiner, D. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 208 KB

english, 2007

19

The efficacy of benzimidazole drugs against Plasmodium falciparum in vitro

Tina S. Skinner-Adams, Timothy M.E. Davis, Linda S. Manning, Wayne A. Johnston

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1997

Language:

english

File:

PDF, 620 KB

english, 1997

20

Mollemycin A: An Antimalarial and Antibacterial Glyco-hexadepsipeptide-polyketide from an Australian Marine-Derived Streptomyces sp. (CMB-M0244)

Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S., Capon, Robert J.

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 331 KB

english, 2014

21

Adaption of the [ 3 H]-hypoxanthine uptake assay for in vitro cultured Plasmodium knowlesi malaria parasites

Arnold, Megan S. J., Engel, Jessica A, Chua, Ming Jang, Fisher, Gillian M, Skinner-Adams, Tina S, Andrews, Katherine T

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 472 KB

english, 2016

22

Lead Compounds for Antimalarial Chemotherapy: Purine Base Analogs Discriminate between Human and P. Falciparum 6-Oxopurine Phosphoribosyltransferases

Keough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin, Brereton, Ian M., Guddat, Luke W., de Jersey, John

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

23

The Aminopeptidase Inhibitor CHR-2863 Is an Orally Bioavailable Inhibitor of Murine Malaria

Skinner-Adams, T. S., Peatey, C. L., Anderson, K., Trenholme, K. R., Krige, D., Brown, C. L., Stack, C., Nsangou, D. M. M., Mathews, R. T., Thivierge, K., Dalton, J. P., Gardiner, D. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 811 KB

english, 2012

24

Erratum to “Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites” [Int. J. Parasitol. Drugs Drug Res. 5 (2015) 117–126]

Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D.M., Ng, Susanna S., Fairlie, David P., Skinner-Adams, Tina, Andrews, Katherine T.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2016

Language:

english

File:

PDF, 109 KB

english, 2016

25

Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold

Schwartz, Brett D., Skinner-Adams, Tina S., Andrews, Katherine T., Coster, Mark J., Edstein, Michael D., MacKenzie, Donna, Charman, Susan A., Koltun, Maria, Blundell, Scott, Campbell, Anna, Pouwer, Re

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 991 KB

english, 2015

26

HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study

Porter, K. A., Cole, S. R., Eron, J. J., Zheng, Y., Hughes, M. D., Lockman, S., Poole, C., Skinner-Adams, T. S., Hosseinipour, M., Shaffer, D., D'Amico, R., Sawe, F. K., Siika, A., Stringer, E., Curri

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

27

Plasmodium falciparum gametocytes: with a view to a kill

BUTTERWORTH, ALICE S., SKINNER-ADAMS, TINA S., GARDINER, DON L., TRENHOLME, KATHARINE R.

Journal:

Year:

2013

Language:

english

File:

PDF, 288 KB

english, 2013

28

In vitro growth inhibition of Plasmodium falciparum by retinol at concentrations present in normal human serum

T.M.E. Davis, T.S. Skinner-Adams, J. Beilby

Journal:

Year:

1998

Language:

english

File:

PDF, 248 KB

english, 1998

29

Characterization of the Plasmodium falciparum M17 Leucyl Aminopeptidase: A PROTEASE INVOLVED IN AMINO ACID REGULATION WITH POTENTIAL FOR ANTIMALARIAL DRUG DEVELOPMENT

Stack, C. M., Lowther, J., Cunningham, E., Donnelly, S., Gardiner, D. L., Trenholme, K. R., Skinner-Adams, T. S., Teuscher, F., Grembecka, J., Mucha, A., Kafarski, P., Lua, L., Bell, A., Dalton, J. P.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.26 MB

english, 2007

30

Inhibition of growth in vitro of Plasmodium falciparum by vitamin E (α-tocopherol)

T. Skinner-Adams, T.M.E. Davis, J. Beilby

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1998

Language:

english

File:

PDF, 275 KB

english, 1998

31

Psammaplysin Derivatives from the Balinese Marine Sponge Aplysinella strongylata

Mudianta, I Wayan, Skinner-Adams, Tina, Andrews, Katherine T., Davis, Rohan A., Hadi, Tri A., Hayes, Patricia Y., Garson, Mary J.

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 741 KB

english, 2012

32

Total Synthesis of Thiaplakortone A: Derivatives as Metabolically Stable Leads for the Treatment of Malaria

Pouwer, Rebecca H., Deydier, Sophie M., Le, Phuc Van, Schwartz, Brett D., Franken, Nicole C., Davis, Rohan A., Coster, Mark J., Charman, Susan A., Edstein, Michael D., Skinner-Adams, Tina S., Andrews,

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 432 KB

english, 2014

33

Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases

McGowan, S., Oellig, C. A., Birru, W. A., Caradoc-Davies, T. T., Stack, C. M., Lowther, J., Skinner-Adams, T., Mucha, A., Kafarski, P., Grembecka, J., Trenholme, K. R., Buckle, A. M., Gardiner, D. L.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

34

Antimalarial activity of sera from subjects taking HIV protease inhibitors

Redmond, Andrew M, Skinner-Adams, Tina, Andrews, Katherine T, Gardiner, Donald L, Ray, John, Kelly, Mark, McCarthy, James S

Journal:

Year:

2007

Language:

english

File:

PDF, 218 KB

english, 2007

35

The activity of protease inhibitors against Giardia duodenalis and metronidazole-resistant Trichomonas vaginalis

Linda A. Dunn, Katherine T. Andrews, James S. McCarthy, Janelle M. Wright, Tina S. Skinner-Adams, Peter Upcroft, Jacqueline A. Upcroft

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

36

A novel in vitro image-based assay identifies new drug leads for giardiasis

Hart, Christopher J.S., Munro, Taylah, Andrews, Katherine T., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

37

Plasmodium Gametocyte Inhibition Identified from a Natural-Product-Based Fragment Library

Vu, Hoan, Roullier, Catherine, Campitelli, Marc, Trenholme, Katharine R., Gardiner, Donald L., Andrews, Katherine T., Skinner-Adams, Tina, Crowther, Gregory J., Van Voorhis, Wesley C., Quinn, Ronald J

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

38

Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939

Sumanadasa, S. D. M., Goodman, C. D., Lucke, A. J., Skinner-Adams, T., Sahama, I., Haque, A., Do, T. A., McFadden, G. I., Fairlie, D. P., Andrews, K. T.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 911 KB

english, 2012

39

An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

Hesping, Eva, Skinner-Adams, Tina S., Fisher, Gillian M., Kurz, Thomas, Andrews, Katherine T.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2020

File:

PDF, 1.30 MB

2020

40

In vitro antimalarial activity of trovafloxacin, a fourth-generation fluoroquinolone

J Hamzah, T Skinner-Adams, T.M.E Davis

Journal:

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

41

Comparison ofPlasmodium falciparumtransfection methods

Tina S Skinner-Adams, Paula M Lawrie, Paula L Hawthorne…

Journal:

Malaria Journal

Year:

2003

Language:

english

File:

PDF, 467 KB

english, 2003

42

Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria

Andrews, K. T., Fairlie, D. P., Madala, P. K., Ray, J., Wyatt, D. M., Hilton, P. M., Melville, L. A., Beattie, L., Gardiner, D. L., Reid, R. C., Stoermer, M. J., Skinner-Adams, T., Berry, C., McCarthy

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

43

Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

Peatey, C. L., Andrews, K. T., Eickel, N., MacDonald, T., Butterworth, A. S., Trenholme, K. R., Gardiner, D. L., McCarthy, J. S., Skinner-Adams, T. S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

44

Effect of clinically approved HDAC inhibitors on Plasmodium , Leishmania and Schistosoma parasite growth

Chua, Ming Jang, Arnold, Megan S.J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Späth, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S., Andrews, Katherine T.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

45

Identification of Phosphinate Dipeptide Analog Inhibitors Directed against the Plasmodium falciparum M17 Leucine Aminopeptidase as Lead Antimalarial Compounds

Skinner-Adams, Tina S., Lowther, Jonathan, Teuscher, Franka, Stack, Colin M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Trenholme, Katharine R., Dalton, John P., Gardiner, Donald L.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 245 KB

english, 2007

46

Malaria transfection and transfection vectors

Donald L. Gardiner, Tina S. Skinner-Adams, Tobias Spielmann, Katharine R. Trenholme

Journal:

Trends in Parasitology

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

47

The M17 Leucine Aminopeptidase of the Malaria Parasite Plasmodium falciparum : Importance of Active Site Metal Ions in the Binding of Substrates and Inhibitors

Maric, Selma, Donnelly, Sheila M., Robinson, Mark W., Skinner-Adams, Tina, Trenholme, Katharine R., Gardiner, Donald L., Dalton, John P., Stack, Colin M., Lowther, Jonathan

Journal:

Year:

2009

Language:

english

File:

PDF, 737 KB

english, 2009

48

An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

Tiash, Snigdha, Saunders, Jake, Hart, Christopher J.S., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2020

File:

PDF, 1.21 MB

2020

49

Plasmodium falciparum: Isolate-Specific Radiosensitivity

D.Sean Geoghegan, Tina Skinner-Adams, Timothy M.E. Davis

Journal:

Experimental Parasitology

Year:

2001

Language:

english

File:

PDF, 92 KB

english, 2001

50

Characterization of the effect of retinol on Plasmodium falciparum in vitro

J. Hamzah, T.M.E. Davis, T.S. Skinner-Adams, J. Beilby

Journal:

Experimental Parasitology

Year:

2004

Language:

english

File:

PDF, 3.26 MB

english, 2004

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